Nandrolone Review. Forms and action of the drug. Dosage, Side Effects, Cycles

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Nandrolone Decanoate / Nandrolone Phenylpropionate[edit]

Nandrolone Phenylpropionate
Nandrolone Effects

Nandrolone - chemical name - 19-nortestosterone) is an anabolic steroid that can be formed in the human body after severe or prolonged physical exertion or during pregnancy, and concentration of its major metabolite in urine 19-norandrosterone does not exceed a few nanograms per ml. Nandrolone is most commonly sold in the form of decanoate, rarely in the form of phenylpropionate. Deca Durabolin first appeared on the market in 1962 and is one of the most popular steroids in recent decades, earning a reputation for severe Anabolic activity, and the relatively low incidence of side effects.

Retabolil - Gedeon Richter 50mg / ml. Composition:

  • Nandrolone decanoate - 50 mg
  • Sunflower oil
  • Benzyl alcohol (as preservative and antiseptic)

Deca Durabolin - Organon 25/50 / 100mg / ml. Composition:

  • Nandrolone decanoate - 25/50/100 mg
  • Peanut oil
  • Benzyl alcohol (as preservative and antiseptic)

Structurally nandrolone differs from Testosterone by the absence of carbon at 19th position (hence the name is 19-nortestosterone), and this makes it more similar to progestins. Due to its progestin nature, retabolil exhibits significantly less Androgenic activity in comparison with Testosterone, but interaction with the progesterone receptor entails a number of side effects, which are described below.

Another difference is that the Testosterone in the body is gradually converted by the enzyme 5 alpha-reductase into powerful androgen - Dihydrotestosterone, which is responsible for most of the development of side effects. Nandrolone, on the contrary turns 5-alpha reductase in a very weak androgen - dihydronandrolone which has almost no effect on the body and does not cause side effects. However, this may be one of the reasons for the libido decrease during the cycle (due to falling of blood androgen level). Also, dihydronandrolone is sometimes included in some anabolic supplements.

Steroid profile[edit]

  • Anabolic Activity - 150% of Testosterone
  • Androgenic Activity - 30% of Testosterone
  • Aromatization (conversion to estrogen) - minimum
  • Hepatotoxicity – Low
  • Method for use - Injection
  • Duration - 15 days (half-life - 7 days)
  • The recommended dose - 50 mg every 5 days (optimally-minimal version)
  • Detection time - up to 18 months
  • Suppression of Testosterone - the average-high (due to the progestin nature)

Effects[edit]

  • Severe muscle growth (during one cycle you can gain up to 8 kg of muscle mass with minimal rollback phenomenon)
  • Bone strengthening (previously used to treat osteoporosis) and ligaments (stimulates Collagen synthesis)
  • Eliminating joint pain, due to increased production of synovial fluid (joint lubricant)
  • The increase of erythrocyte mass of blood, resulting the improvement of oxygen transport. As a result - more stamina
  • Enhancing the immune system (applies even to people with AIDS)
  • Conversion to estradiol without the enzyme aromatase
  • Improving intestinal absorbability of Amino acids and other nutrients

Nandrolone has a relatively low chance of side effects. As a result of low androgenic activity, side effects such as acne, alopecia, body hair growth hardly occur. Nevertheless, they are possible, just like when using any steroid, but in the case of nandrolone it occurs only when exceeding the recommended doses by several times.

Retabolil has very low conversion rates (flowing without aromatase) into estrogens, as research showed it is 5 times lower than Testosterone. The highest level of conversion is in the liver, while the main place where the transformation takes place is unavailable for this process. Because of this, Deca Durabolin has no side effects associated with estrogen (gynecomastia, water retention). Estrogenic activity of the steroid occurs only at very high doses.

The above described properties explain why Deca Durabolin is one of the most popular anabolic steroids to date, including for men with the aim of gaining lean muscle.

Side effects[edit]

It has been observed that Nandrolone is capable of binding to progestin receptors (approximately 20% of the injected material) , it is because of a remote carbon atom in 19th position. Almost all of the 19-nor anabolic steroids exhibit progestin activity.

In addition, retabolil caused following side effects during studies:

  • Headache - 20%
  • Rhinitis (runny nose) - 15%
  • Back pain - 15%
  • Rash - 10%

In addition, during the cycle sometimes there are: rise in blood pressure, abdominal pain, irritability, headaches, depression and some other complications.

Progestin side effects[edit]

When binding to progestin receptors of the pituitary, Nandrolone causes increased production of prolactin and suppresses the secretion of gonadotropins. Prolactin is largely similar to estrogen, its effect is manifested by decreased production of Testosterone, a slight increase in fat mass and in rare cases gynecomastia.

Reducing the concentration of Testosterone in the blood and activation of the progesterone receptor may very often lead to a decreased libido, which can be restored within a month after the cycle (called Deca Dick).

Progestin activity and its consequences (particularly sluggish erection, inhibition of sexual desire, and rarely gynecomastia) - is probably the main disadvantage of Deca Durabolin, but it can be successfully prevented. To do this, inhibitors of prolactin are used: bromocriptine, or more modern and secure - Cabergoline (Dostinex). These drugs significantly increase sexual desire during the cycle (and beyond), enhance orgasm and shorten recovery time between sexual acts. It has also been shown that Winstrol has antiprogestin activity (research of Ellis AJ, Cawston TE, 1994), so they can be combined very well together.

Retabolil cycle[edit]

Nandrolone Cycle

This drug acts slowly. Anabolic effect during the Retabolilum cycle unfolds gradually, while there is a significant, but not dramatic muscle growth. From this it follows that nandrolone cycle should be longer than other anabolic agents. When using equivalent doses of the same duration and Testosterone causes approximately twice more weight gain. However, Testosterone is peculiar to a more pronounced pullback phenomenon. Nandrolone cycle usually lasts for 8-10 weeks. However, some performing athletes use it up to six months, gradually increasing the dosage. Nandrolone cycle is recommended with a mandatory use of Testosterone to avoid progestin effects and consequences of low Testosterone (low libido, weak erection).

Injections of nandrolone are usually made 1 time per week. Considering the activity period - 15 days, there is no need to do 2 injections of Retabolilum per week. But if the weekly amount of administered drug is large, it is often divided into two or three injections. The recommended dose of nandrolone is 200 mg per week or more, while the familiarity with the drug should be started with lower dosages. The maximum dose is 600 mg per week, but with increase of dose increases the risk of side effects. You can get great results if you do 2 cycles with breaks at reasonable doses, rather than one large dose.

  • Do not make the cycle longer than 8 weeks without any additional drugs. At long cycles you should use human chorionic gonadotropin. If during a long cycle HCG is not used, then its required to be taken at the end of the cycle before the PCT, but not during PCT.
  • To eliminate the activity of progesterone it is necessary to include bromocriptine, starting from the second and ending in 2-3 weeks after the final injection of nandrolone. It should be taken at 1.25 mg twice a day. Instead of bromocriptine, it is preferable to use a more modern Cabergoline at 0.25 mg every fourth day throughout the cycle, and 2-3 weeks after.
  • In addition, for the restoration of the hypothalamic-pituitary-testes axis, Clomid (clomiphene citrate) is applied from the beginning of the last week of the cycle and it ends 2-4 weeks after, at 50-100 mg with gradual withdrawal. Tamoxifen is not recommended because it increases sensitivity and expands the population of progesterone receptors.
  • You can include Winstrol in the course from the second and to the last week for the suppression of prolactin and reducing progestin activity.

Instead of gonadotropin, Testosterone boosters can be used, but this is less efficient.

  • For maximum effect, take a complex of Sports nutrition for muscle mass gain and follow a diet for muscle mass gain.
  • Retabolilum cycle must be agreed with a specialist.

Combined cycle[edit]

It should be noted that the Retabolilum only cycle has many disadvantages, such as loss of libido, slow activity, the suppression of natural Testosterone, and others. These disadvantages can be eliminated if you add Testosterone in the cycle. This is the gold standard of using nandrolone, it is not recommended to use this steroid without Testosterone. As practice shows, nandrolone cycle needs Testosterone, which should be 2 times more. Nandrolone is combined well with the following medications:

The most optimal cycle for a week: