Testosterone Propionate Review. Action of the drug. Dosage, Side Effects, Cycles, How to take.

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Testosterone Propionate[edit]

Testosterone Propionate effects

Testosterone Propionate is one of the most popular steroids in bodybuilding. Testosterone propionate is used for the development of muscle mass and strength, but because of the nature of action, it is often used during cutting. It is one of testosterone esters. Testosterone is a hormone that acts as the basic molecule for most hormonal (androgen) agents. By changing the testosterone molecule (adding or removing atoms), it is synthesized by one or the other drug. For example, testosterone propionate is a testosterone molecule to which a propionic acid ester is added, it determines the pharmacological properties and characteristics of the substance effect.

Steroid profile[edit]

  • Anabolic Activity - 100% of Testosterone
  • Androgenic Activity - 100% of testosterone (high)
  • Aromatization (conversion to estrogen) - High (there is a need to antiestrogens)
  • The suppression of the hypothalamic-pituitary-testes - expressed
  • Hepatotoxicity - no
  • A method of use - Injection
  • Duration - 2-3 days
  • Detection time - 40 days

The action of testosterone propionate[edit]

  • Specifically, it initiates gene transcription, whereby changes the nitrogen balance in positive way.
  • Increases IGF in muscle and liver
  • Causes proliferation of satellite cells in muscle tissue, due to which there is hyperplasia and muscle recovery

It should be noted that all the esters have similar mechanisms of action, the difference is in the activity and the primary focus of action.


  • Increased muscle mass
  • Fat burning
  • Increased muscle definition
  • Increased power performance
  • Increased libido
  • Reduced risk of heart ischemia and coronary disease

It features short duration of action. Injections are usually made every other day. This is one of the main disadvantages of propionate application, as compared with its longer lived analogs, such as enanthate. The second major disadvantage is the higher cost compared to the same enanthate. It can be used for both muscle mass gain and foe cutting.

Another feature of the agent is that, with properly selected doses, does not retain water in the body. That’s why testosterone propionate does not cause a sharp increase in body weight of 5-6 kg in a couple of weeks, unlike using enanthate. However, gained muscle mass with propionate is leaner and better. Once in the body, it is rapidly absorbed into the bloodstream, so its action can be felt after the first injection. For the above reasons, when it comes weight gain, athletes prefer enanthate. Propionate is more used for cutting. It suits athletes with any skill levels, from beginners to the most experienced.


It can be used as the only steroid in the cycle, but the best effect is achieved when combined with other steroids. Recommend dosage is 50 mg of propionate every other day for those who start using anabolic agents. The usual dose for more experienced athletes is 100 mg of propionate daily.

Be sure to take anti-estrogens, such as Proviron or aromatase inhibitors in the normal way, starting from the second week, to avoid the development of gynecomastia, water retention, and other estrogen effects. After that, post-cycle therapy should be done, usually using Tamoxifen. Also, cortisol blockers are recommended to preserve gained weight. Be sure to follow the diet for weight gain and take Sports nutrition.

Combined cycle[edit]

During cutting it is well combined with Stanozolol, Trenbolone acetate, Masteron, Primobolan, and some other drugs. Propionate is a part of testosterone ester mixture, just like Sustanon or Omnadren, as a compulsory component it makes you feel the action immediately.

An example cutting cycle for begginer "chemists" based on propionate:

  • Propionate 50 mg every other day
  • Winstrol 30 mg per day, starting at 10 mg, and adjusting the dose to the optimal for 1 week.
  • After 6 weeks, you should stop taking anabolic agents, and start PCT after 3-4 days.

Synergistic effect of drugs appears in this cycle, which means that the total effect of their simultaneous use is more than a simple sum of the effects when they are used each individually. Also, the risk of side effects is reduced. Some experienced athletes make local injection of propionate into the target muscle, for example in the biceps, deltoids, the lower leg, but the effectiveness of this way is not proven.

Any form of steroid has only resorptive effect, and there is no local effect on the muscle. If the agents stimulated local hypertrophy of muscle cells when injected intramuscularly, it would be possible to observe asymmetrical growth, superficially similar to the results obtained using synthol.

Side effects[edit]

The most frequent complaints are pain, irritation and redness at the injection site, that even more aggravated by the need in the high frequency of injections. Also, increased aggression.

The side effects of testosterone propionate are due to the fact that it is easily converted and aromatized to estrogens and Dihydrotestosterone, as any testosterone ester in high doses may cause:

  • Gynecomastia
  • Acne
  • Alopecia
  • Hirsutism (body hair growth)
  • Enlarged prostate (especially in the elderly)
  • Masculinization (women)

The drug suppresses the body's own testosterone production, which is usually recovered at the end of the cycle in 2-3 months. During long-term cycles it is necessary to introduce gonadotropin of 500 IU, once per week, starting at 2nd week. Practice shows that in moderate doses it does not affect either the liver or kidneys, or any other organs. It is not recommended for women, because of its high Androgenic activity.